发明名称 |
PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT |
摘要 |
Pyrimidine derivatives of general formula (I) or nontoxic salts thereof, useful as intermediates for the synthesis of drugs and/or as drugs, particularly elastase inhibitors. In formulas (I) and (II) R<1> is H or F; R<2> is -CH(OR<3>)2, CHO, COOH, alkoxycarbonyl, furan-2-yl, a group of general formula (II), or the like; R<3> is Me or Et; and R<4> is alkyl, phenyl, (substituted) benzyl, or the like.
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申请公布号 |
WO0123361(A1) |
申请公布日期 |
2001.04.05 |
申请号 |
WO2000JP06601 |
申请日期 |
2000.09.26 |
申请人 |
ONO PHARMACEUTICAL CO., LTD.;KOJIMA, TSUTOMU;OKADA, TAKANORI;HACHIYA, KATSUTOSHI;MOTOI, TAKAHIRO;HASHIMOTO, SHINSUKE |
发明人 |
KOJIMA, TSUTOMU;OKADA, TAKANORI;HACHIYA, KATSUTOSHI;MOTOI, TAKAHIRO;HASHIMOTO, SHINSUKE |
分类号 |
A61P1/02;A61P9/00;A61P11/00;C07D239/36;C07D405/06;C07D413/12;(IPC1-7):C07D239/36;A61K31/505;A61K31/506 |
主分类号 |
A61P1/02 |
代理机构 |
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代理人 |
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地址 |
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