METHODS OF PRODUCING CLONED AND TRANSGENIC MAMMALS

摘要

The invention features a method of promoting the development of a pre-natal non-human mammal. The method includes: forming a reconstructed embryo in association with at least one extra embryonic cell, e.g., a tetraploid cell; transferring the reconstructed embryo into a recipient mammal; and allowing the embryo to develop, to thereby promote development of the mammal.