CREATION OF VARIABLE LENGTH AND SEQUENCE LINKER REGIONS FOR DUAL-DOMAIN OR MULTI-DOMAIN MOLECULES
摘要
Disclosed are methods and compositions for creating a DNA, RNA or protein molecule with two or more nucleic acid or polypeptide domains, respectively, joined by a linker region. These methods are used to generate random linker libraries of nucleic acids that encode dual-domain or multi-domain polypeptides. The linker regions are characterized by both length and sequence variability.
申请公布号
WO0123543(A1)
申请公布日期
2001.04.05
申请号
WO2000US25965
申请日期
2000.09.22
申请人
LARGE SCALE BIOLOGY CORPORATION;REINL, STEPHEN, J.;LINDBO, JOHN, A.;TURPEN, THOMAS
发明人
REINL, STEPHEN, J.;LINDBO, JOHN, A.;TURPEN, THOMAS