发明名称 |
Vectors and methods for providing cells with additional nucleic acid material integrated in the genome of said cells |
摘要 |
The present invention provides novel elements for improving genetic engineering techniques for producing recombinant nucleic acid molecules and/or recombinant cells. The novel elements are capable of integrating desired nucleic acid material into other nucleic acid materials, specifically into the genome of a host cell. The novel elements are derived from or based on transposons, in particular from the Tc/Mariner superfamily. In particular, the essential elements of Tc1 enabling excision and pasting of the desired nucleic acid material are provided, together with the relevant transposase activity in cis or in trans. |
申请公布号 |
AU731615(B2) |
申请公布日期 |
2001.04.05 |
申请号 |
AU19970016746 |
申请日期 |
1997.02.07 |
申请人 |
HET NEDERLANDS KANKER INSTITUUT |
发明人 |
RONALD HANS ANTON PLASTERK;JAN CHRISTIAAN VOS |
分类号 |
C12N15/09;A61K48/00;C07K14/435;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/22;C12N15/90;(IPC1-7):C12N15/90 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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