发明名称 |
Benzyloxy-substituted, fused N-heterocycles, processes for their preparation, and their use as bradykinin receptor antagonists |
摘要 |
Benzyloxy-substituted, fused N-heterocycles, because of their ability to act as bradykinin receptor antagonists, have been found to be useful as therapeutics for the treatment and prevention of liver cirrhosis or Alzheimer's disease. This application describes such compounds, as well as processes for their preparation and use. The compounds according to this invention include compounds of formula (I)in which B, D, R1, and R2 have the meanings indicated herein.
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申请公布号 |
US6211196(B1) |
申请公布日期 |
2001.04.03 |
申请号 |
US19980048305 |
申请日期 |
1998.03.26 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
HEITSCH HOLGER;WAGNER ADALBERT;WIRTH KLAUS;SCHOELKENS BERNWARD |
分类号 |
C07D215/24;A61K31/395;A61K31/47;A61K31/495;A61P1/16;A61P43/00;C07D215/26;C07D241/36;C07D401/12;C07D405/12;(IPC1-7):C07D401/00;C07D217/00;C07D215/00;A61K31/505;C07P237/00 |
主分类号 |
C07D215/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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