发明名称 Muscarinic receptor agonists
摘要 A compound of Formula (I):wherein R is independently selected from (CH2)9-12, (CH2CH2)2O, (CH2CH2)3O2, (CH2CH2)4O3, (CH2CH2)5O4, (CH2CH2)6O5 or (CH2CH2CH2)3O2; or an acid addition salt or hydrate thereof. The compounds, with improved water solubility, have unusually high affinity for muscarinic receptors, and exhibit agonist activity useful in the treatment of neurological and other disorders, in which stimulating cholinergic activity is desirable.
申请公布号 US6211204(B1) 申请公布日期 2001.04.03
申请号 US20000483334 申请日期 2000.01.14
申请人 UNIVERSITY OF TOLEDO 发明人 MESSER WILLIAM S.;CAO YANG;RAJESWARAN WALAJAPET G.
分类号 C07D417/14;(IPC1-7):A61K31/34;C07D417/00 主分类号 C07D417/14
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