| 发明名称 |
Synthesis of oligonucleotides |
| 摘要 |
Synthetic processes are provided for the solution phase synthesis of oligonucleotides, especially phosphorothioate oligonucleotides, and intermediate compounds useful in the processes. Intermediates having structureare prepared in accord with preferred embodiments.
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| 申请公布号 |
US6211350(B1) |
申请公布日期 |
2001.04.03 |
| 申请号 |
US19990395948 |
申请日期 |
1999.09.14 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
RAVIKUMAR VASULINGA;COLE DOUGLAS L. |
| 分类号 |
C07F9/146;C07F9/24;C07H21/00;C07H23/00;(IPC1-7):C07H19/00;C07H21/02;C07H21/04 |
主分类号 |
C07F9/146 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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