发明名称 |
PROCESS FOR THE PRODUCTION OF 2-SUBSTITUTED 4,6-DIALKOXYPYRIMIDINES |
摘要 |
A process is disclosed for the production of 2-substituted 4,6-dialkoxypyrimidines of the formula: (see formula I) wherein R1 and R2 each independently represent a lower alkyl group, and R3 represents an R4-O-, R4-S- or group, in which R4 is lower alkyl and R5 is hydrogen, lower alkyl or phenyl. The process includes cyclizing a cyanimidate of the general formula: (see formula II) with a hydrogen halide to form a halopyrimidine derivative of the general formula: (see formula III) The latter is then converted either with a compound of the formula: M-R3 (IV) or with an alkyl amine of the general formula: (see formula V) into the end product of general formula I.
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申请公布号 |
CA2083790(C) |
申请公布日期 |
2001.04.03 |
申请号 |
CA19922083790 |
申请日期 |
1992.11.25 |
申请人 |
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发明人 |
ESCHER, ANDRE;PREVIDOLI, FELIX |
分类号 |
C07D239/52;C07D239/50;C07D239/54;C07D239/545;C07D239/60;(IPC1-7):C07D239/52 |
主分类号 |
C07D239/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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