Substituted isoquinolines as ultra short acting neuromuscular blockers and their use in therapy

摘要

Ultrashort acting neuromuscular blocking agents of Formula (I), which are useful as skeletal muscle relaxants during emergency intubation procedures, routine surgery and post-operative settings, are disclosed, wherein: X is halogen h is from 1 to 2 Y is hydrogen or methoxy Z1 and Z2 are methyl W1 and W2 are carbon A is a pharmaceutically acceptable anion