发明名称 |
INDOLE DERIVATIVES AS 5-HT RECEPTOR ANTAGONIST |
摘要 |
<p>A compound of formula (I) or a salt thereof:wherein:P1 is pyridiyl;P2 is phenyl;A is a bond or a chain of 1 to 5 atoms optionally substituted by C1-6 alkyl;R1 and R2 groups are each independently hydrogen, C1-6alkyl optionally substituted by NR12R13, C2-6alkenyl, C2-6alkynyl, cyano, halogen, CF3, NR12R13, CHO, OCF3, COR14, CH2OR14 or OR14 where R12, R13 and R14 are independently hydrogen or C1-6alkyl;n and m are independently 0, 1 or 2;R3 is hydrogen or C1-6 alkyl;R4 is a group of formula (i):in which:R6 and R7 are independently hydrogen, C1-6 alkyl optionally substituted by one or more fluorine atoms, C1-6alkylthio, C1-6alkoxy or halogen.</p> |
申请公布号 |
GR3035075(T3) |
申请公布日期 |
2001.03.30 |
申请号 |
GR20000402763T |
申请日期 |
2000.12.13 |
申请人 |
SMITHKLINE BEECHAM PLC |
发明人 |
GASTER, LARAMIE, M.;WYMAN, PAUL, A.;MULHOLLAND, KEITH, R.;DAVIES, DAVID, T.;DUCKWORTH, DAVID, M.;FORBES, IAN, T.;JONES, GRAHAM, E. |
分类号 |
A61K31/40;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/475;A61K31/495;A61K31/50;A61K31/505;A61P25/00;A61P25/30;A61P43/00;C07D401/12;C07D401/14;C07D403/12;C07D405/14;C07D409/14;C07D413/12;C07D417/14;(IPC1-7):C07D401/12 |
主分类号 |
A61K31/40 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|