发明名称 |
Adenoviruses having altered hexon proteins which present epitopes that are not recognised by neutralizing antibodies to the unmodified adenovirus of another serotype |
摘要 |
Described are adenoviruses in which a portion of the hexon protein is changed and preferably, wherein at least a portion of at least one of the L1 and L2 and/or L4 loop regions of the hexon of the adenovirus of a first serotype is removed and replaced with at least a portion of one of the L1 and L2 loop regions of the hexon of a second serotype of at least
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申请公布号 |
NZ336829(A) |
申请公布日期 |
2001.03.30 |
申请号 |
NZ19980336829 |
申请日期 |
1998.01.22 |
申请人 |
GENETIC THERAPY, INC |
发明人 |
ROY, SOUMITRA |
分类号 |
C12N15/09;A61K48/00;C12N7/00;C12N7/01;C12N15/861;(IPC1-7):C12N7/01;A61K35/76;C12N15/86 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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