摘要 |
This invention relates to the gene cluster for aclacinomycin biosynthesis being included in a 7kb <i>Xho</i>I-<i>Not</i>I fragment and a flanked 8.5kb <i>Bgl</i>II fragment derived from <i>Streptomyces galilaeus</i>, and the use of the genes included therein to obtain hybrid antibiotics, or to increase yields of aclacinomycins or related antibiotics. |