| 发明名称 |
CAPSID-MODIFIED RECOMBINANT ADENOVIRUS AND METHODS OF USE |
| 摘要 |
The present invention describes a recombinant adenoviral vector in which a single-chain antibody has been introduced into the minor capsid proteins, pIIIa or pIX, so that the adenoviral vector can be targeted to a particular cell type. Additionally disclosed is a method of using the recombinant adenoviral vector in targeted gene therapy.
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| 申请公布号 |
CA2384827(A1) |
申请公布日期 |
2001.03.29 |
| 申请号 |
CA20002384827 |
申请日期 |
2000.09.22 |
| 申请人 |
THE UAB RESEARCH FOUNDATION |
发明人 |
CURIEL, DAVID T. |
| 分类号 |
C12N15/09;A61K31/52;A61K36/06;A61K48/00;A61P35/00;C07K14/075;C12N7/00;C12N15/861;C12R1/92;(IPC1-7):A61K48/00;C12N15/00;C12N15/63;C12N15/86 |
主分类号 |
C12N15/09 |
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