发明名称 |
TUMOR SPECIFIC HUMAN MONOCLONAL ANTIBODIES AND METHODS OF USE |
摘要 |
The invention provides tumor-specific human monoclonal antibodies and functional fragments. Also provided are nucleic acids encoding tumor-specific human monoclonal antibodies and functional fragments. A method for reducing neoplastic cell proliferation is also provided. The method consists of administering an effective amount of a tumor-specific human monoclonal antibody or functional fragment. Also provided is a method of detecting a neoplastic cell in a sample. The method consists of contacting a cell with a tumor-specific monoclonal antibody or functional fragment and detecting the specific binding of the human monoclonal antibody or functional fragment to the sample. |
申请公布号 |
WO0032635(A9) |
申请公布日期 |
2001.03.29 |
申请号 |
WO1999US28485 |
申请日期 |
1999.12.02 |
申请人 |
IXSYS, INCORPORATED |
发明人 |
WATKINS, JEFFRY, D.;HUSE, WILLIAM, D. |
分类号 |
A61K47/48;C07K16/30;(IPC1-7):C07K16/30;A61K39/395;G01N33/577;G01N33/574;A61P35/00;C12N15/13;C12N5/20 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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