发明名称 |
Gastroretentive controlled release microspheres for improved drug delivery |
摘要 |
There is provided a drug delivery composition for the controlled release of an active agent in the stomach environment over a prolonged period of time, which comprises a microsphere comprising an active ingredient in the inner core of the microsphere and (i) a rate controlling layer of a water insoluble polymer and (ii) an outer layer of a bioadhesive agent in the form of a cationic polymer.
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申请公布号 |
US6207197(B1) |
申请公布日期 |
2001.03.27 |
申请号 |
US19990424145 |
申请日期 |
1999.11.18 |
申请人 |
WEST PHARMACEUTICAL SERVICES DRUG DELIVERY & CLINICAL RESEARCH CENTRE LIMITED |
发明人 |
ILLUM LISBETH;PING HE |
分类号 |
A61K9/00;A61K9/16;A61K9/50;A61K9/52;A61K31/4164;A61K31/426;A61K31/663;A61K47/36;A61K47/38;A61P1/04;A61P31/04;(IPC1-7):A61K9/16 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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