| 发明名称 |
Activin receptor-like kinases, ALK-3 and ALK-6, and nucleic acids encoding them |
| 摘要 |
The invention relates to two members of the receptor family referred to as activin-like kinases. These two members are referred to as ALK-3 and ALK-6. The proteins have activin/TGF-beta type I receptor functionality, and may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain V1B, and/or a GTKRYM sequence in subdomain VIII.
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| 申请公布号 |
US6207814(B1) |
申请公布日期 |
2001.03.27 |
| 申请号 |
US19990382256 |
申请日期 |
1999.08.24 |
| 申请人 |
LUDWIG INSTITUTE FOR CANCER RESEARCH |
发明人 |
MIYAZONO KOHEI;TEN DIJKE PETER;FRANZEN PETRA;YAMASHITA HIDETOSHI;HELDIN CARL-HENRIK |
| 分类号 |
C12N15/09;A61K38/00;A61K38/45;A61P1/16;A61P29/00;A61P35/00;C07K14/71;C07K14/72;C07K16/28;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;C12R1/91;(IPC1-7):C12N15/12 |
主分类号 |
C12N15/09 |
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