发明名称 |
Method for inducing a systemic immune response to an HIV antigen |
摘要 |
A method is provided for inducing a systemic immune response to an antigen selected from inactivated HIV I and HIV II antigens in a mammal. The method comprises orally administering lyophilized multilaminar liposomes containing the antigen. The liposomes have a size of from 20 nm to 20 microns. The antigen-containing liposomes are absorbed in the Peyer's patches of the gut. Sufficient antigen-containing liposomes are taken up by macrophages in the Peyer's patches to induce a systemic immune response to the antigen.
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申请公布号 |
US6207185(B1) |
申请公布日期 |
2001.03.27 |
申请号 |
US19970948568 |
申请日期 |
1997.10.10 |
申请人 |
BIO-SPHERE TECHNOLOGY |
发明人 |
SEE JACKIE R.;SEE DARRYL M. |
分类号 |
A61K9/127;A61K9/48;A61K9/52;A61K39/12;A61K39/125;A61K39/21;A61K39/29;A61K39/39;(IPC1-7):A61K9/127;A61K9/133 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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