发明名称 |
Kinesin motor modulators derived from the marine sponge Adocia |
摘要 |
This invention provides novel compounds derived from a marine sponge, Adocia sp., that specifically modulat kinesin activity by targeting the kinesin motor domain and mimicking the activity a microtubule. The compounds act as potent anti-mitogens are useful in a wide variety of in vitro and in vivo applications.
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申请公布号 |
US6207403(B1) |
申请公布日期 |
2001.03.27 |
申请号 |
US19990226772 |
申请日期 |
1999.01.06 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
GOLDSTEIN LAWRENCE S. B.;FAULKNER DAVID JOHN;SAKOWICZ ROMAN;BERDELIS MICHAEL S.;BLACKBURN CHRISTINE L.;HOPMANN CORDULA |
分类号 |
A61K31/56;A61K31/255;A61K31/58;A61P35/00;A61P43/00;C07C303/00;C07C305/06;C07D313/06;C07J53/00;C07J71/00;C12Q1/42;G01N33/50;(IPC1-7):C12Q1/42;C12Q1/68;G01N33/53 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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