发明名称 Pneumatically assisted electrospray device with alternating pressure gradients for mass spectrometry
摘要 An apparatus for producing gas-phase ions from a sample compound in a carrier liquid. The electrospray needle (or capillary) of the present invention includes a central metal tube which carries the liquid containing the sample compound. The central tube is surrounded by a plurality of tubes which transport a nebulizing gas. The nebulizing gas tubes are placed symmetrically around the outside of the liquid containing tube. The nebulizer of the present invention produces a symmetric, non-annular gas flow which has variations in pressure around the circumference of the central tube. The pressure variations of the nebulizing gas flow produce additional shear forces on the liquid emerging from the central tube. This assists in forming a uniform electrospray of droplets from the liquid at lower nebulizing gas flow rates, thereby reducing the disadvantageous effects of the higher gas flow rates used in the art. The symmetric arrangement of the nebulizing gas tubes provides support for the central sample carrying tube, thereby reducing the alignment problems found in prior art devices, and enhancing uniformity of the electrospray.
申请公布号 US6207955(B1) 申请公布日期 2001.03.27
申请号 US19980162261 申请日期 1998.09.28
申请人 VARIAN, INC. 发明人 WELLS GREGORY J.;TONG ROGER C.;YEE PETER P.
分类号 G01N27/64;G01N27/62;G01N30/72;H01J49/04;(IPC1-7):B01D59/44;H01J49/00 主分类号 G01N27/64
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