| 发明名称 |
Dna encoding a human subunit 5-ht3-c of the 5-ht3 serotonin receptor |
| 摘要 |
DNA encoding human 5-HT3-C has been cloned and characterized. The recombinant protein is capable of forming biologically active human 5-HT3-C protein. The cDNA has been expressed in recombinant host cells that produce active recombinant protein. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified. |
| 申请公布号 |
AU7058300(A) |
申请公布日期 |
2001.03.26 |
| 申请号 |
AU20000070583 |
申请日期 |
2000.08.14 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
ADRIENNE E. DUBIN;MARK G ERLANDER;ARNE HUVAR;RENE HUVAR;LUKAS K. BUEHLER |
| 分类号 |
G01N33/50;A61K31/7088;A61K38/00;A61K45/00;A61K48/00;A61P1/04;A61P1/08;A61P1/10;A61P3/04;A61P3/10;A61P9/06;A61P9/12;A61P9/14;A61P11/06;A61P11/08;A61P13/10;A61P15/10;A61P25/04;A61P25/06;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P29/00;A61P37/08;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12P21/08;G01N33/15;G01N33/566 |
主分类号 |
G01N33/50 |
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