| 摘要 |
<p>The present invention provides a process for the production of two molecules of 4-aryl-2 butanols having the general formula 1 given below:Wherein R=H or glucose from the leaves of Taxus wallichiana, which comprises:(a) defatting air dried, pulverized leaves with aliphatic hydrocarbon solvents,(b) extracting the defatted leaves with chlorinated solvents and polar solvent successively at room temperature,(b) concentrating the chlorinated solvent soluble faction to a residue and treating the residue with aqueous solution of alkali and extracting with chlorinated solvents,(d) acidifying the alkali layer with mineral acid and extracting with ethyl acetate and concentrating the ethyl acetate phase to give compound of formula 1 where R=H,(e) concentrating the polar solvent fraction from step (b) to a residue and treating the residue with aqueous solution of alkali and extracting with chlorinated solvent, and(f) acidifying the alkali phase with mineral acid and extracting with ethyl acetate and concentrating the ethyl acetate to give compound of formula 1 where R=glucose.</p> |
