A GENE ENCODING A NOVEL THREONYL-tRNA SYNTHETASE, ITS USES AND THE PREPARING METHODS

摘要

The present invention relatives to a polynucleotide sequence encoding a novel human threonyl-tRNA synthetase, the invention also relatives to the methods for preparing said polynucleotide and the protein it encoded by recombinant technology, the invention discloses the uses of the human threonyl-tRNA synthetase and the polynucleotide sequence encoding said polypeptide in preparing pharmaceutical composition for treating to the diseases resulting from low or lack of function of human threonyl-tRNA synthetase, such as various tumors. The invention also discloses the methods for preparing antibodies against said polypeptides, screening agonists, as well as their uses in treatment.