发明名称 COMBINATION TREATMENT WITH IL-1RA AND DIARYL SULPHONYL UREA COMPOUNDS
摘要 The invention relates to methods and compositions for treating and preventing interleukin 1 (IL-1) mediated disease states. The methods and compositions use an interleukin 1 receptor antagonist (IL-1ra) polypeptide or variant thereof in combination with a non-steroidal IL-1 processing and release inhibiting agent.
申请公布号 WO0119390(A1) 申请公布日期 2001.03.22
申请号 WO2000IB01192 申请日期 2000.08.28
申请人 PFIZER PRODUCTS INC.;LITTMAN, BRUCE, HENRY;WOODWORTH, THASIA, LOUISE, GOODWIN;DOMBROSKI, MARK, ANTHONY 发明人 LITTMAN, BRUCE, HENRY;WOODWORTH, THASIA, LOUISE, GOODWIN;DOMBROSKI, MARK, ANTHONY
分类号 A61K45/00;A61K31/551;A61K31/64;A61K38/00;A61K38/20;A61P19/02;A61P29/00;A61P43/00;(IPC1-7):A61K38/20 主分类号 A61K45/00
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