发明名称 |
INHIBITORS OF FACTOR XA |
摘要 |
Compounds of formula A Q D E G J X in which D is a direct link, a substitute d or unsubsituted phenyl or naphtyl gourp or a heterocyclic ring system; G is substituted or unsubstituted phenyl or a heterocyclic ring system; X is a substituted or unsubstituted phenyl or naphtyl group or a heterocyclic ring system; and the other variables are as defined in the claims, their salts an d compositions related thereto having activity against mammalian factor Xa are disclosed, The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
|
申请公布号 |
CA2385589(A1) |
申请公布日期 |
2001.03.22 |
申请号 |
CA20002385589 |
申请日期 |
2000.09.15 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
KANTER, JAMES;SONG, YONGHONG;HUANG, WENRONG;SCARBOROUGH, ROBERT M.;JIA, ZHAOZHONG JON;ZHU, BING-YAN |
分类号 |
C07D231/14;A61K31/33;A61K31/415;A61K31/4155;A61K31/4178;A61K31/426;A61K31/427;A61K31/428;A61K31/4439;A61K31/454;A61K31/4545;A61K31/4725;A61K31/496;A61K31/506;A61K31/5377;A61K31/541;A61K31/55;A61K31/551;A61P7/02;A61P7/04;A61P43/00;C07C311/16;C07C311/46;C07C317/40;C07C317/44;C07D213/75;C07D213/81;C07D213/82;C07D217/22;C07D277/20;C07D277/56;C07D333/38;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/10;C07D403/12;C07D403/14;C07D405/12;C07D409/12;C07D409/14;C07D417/04;C07D417/12;C07D417/14;C07D471/04;C07D487/04;C07D521/00;(IPC1-7):C07D231/14 |
主分类号 |
C07D231/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|