发明名称 INHIBITORS OF FACTOR XA
摘要 Compounds of formula A Q D E G J X in which D is a direct link, a substitute d or unsubsituted phenyl or naphtyl gourp or a heterocyclic ring system; G is substituted or unsubstituted phenyl or a heterocyclic ring system; X is a substituted or unsubstituted phenyl or naphtyl group or a heterocyclic ring system; and the other variables are as defined in the claims, their salts an d compositions related thereto having activity against mammalian factor Xa are disclosed, The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
申请公布号 CA2385589(A1) 申请公布日期 2001.03.22
申请号 CA20002385589 申请日期 2000.09.15
申请人 MILLENNIUM PHARMACEUTICALS, INC. 发明人 KANTER, JAMES;SONG, YONGHONG;HUANG, WENRONG;SCARBOROUGH, ROBERT M.;JIA, ZHAOZHONG JON;ZHU, BING-YAN
分类号 C07D231/14;A61K31/33;A61K31/415;A61K31/4155;A61K31/4178;A61K31/426;A61K31/427;A61K31/428;A61K31/4439;A61K31/454;A61K31/4545;A61K31/4725;A61K31/496;A61K31/506;A61K31/5377;A61K31/541;A61K31/55;A61K31/551;A61P7/02;A61P7/04;A61P43/00;C07C311/16;C07C311/46;C07C317/40;C07C317/44;C07D213/75;C07D213/81;C07D213/82;C07D217/22;C07D277/20;C07D277/56;C07D333/38;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/10;C07D403/12;C07D403/14;C07D405/12;C07D409/12;C07D409/14;C07D417/04;C07D417/12;C07D417/14;C07D471/04;C07D487/04;C07D521/00;(IPC1-7):C07D231/14 主分类号 C07D231/14
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