ISOLATION OF MUSCLE-DERIVED STEM CELLS AND USES THEREFOR

摘要

A method for purifying muscle stem cells from a myoblast sample isolated fro m mammalian skeletal muscle is disclosed. Purified muscle stem cells can be us ed for a variety of purposes, including for systemic delivery of muscle protein s and other desired nucleic acid products to a mammal, for gene therapy, in th e treatment muscle diseases, including muscular dystrophies, in the treatment or prophylaxis of inherited or acquired diseases, including genetic diseases an d cancer, and in transplanting bone marrow to a mammal.