发明名称 |
USE OF MULLERIAN INHIBITING SUBSTANCE FOR TREATING EXCESS ANDROGEN STATES |
摘要 |
The present invention provides a method of treating a condition or disease characterized by an excess of one or more androgens, the method comprising administering an effective amount of MIS protein or nucleic acid encoding MI S to a patient. The present invention also provides a method of decreasing the level of one or more androgens to a level below the normal level, the method comprising administering an effective amount of MIS protein or nucleic acid encoding MIS to a patient. The methods of the present invention are particularly well-suited for the treatment of prostatic cancer, polycystic ovarian disease, benign prostatic hypertrophy, and precocious puberty.</SDOA B>
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申请公布号 |
CA2384991(A1) |
申请公布日期 |
2001.03.22 |
申请号 |
CA20002384991 |
申请日期 |
2000.09.14 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
DONAHOE, PATRICIA K.;TEIXEIRA, JOSE;FYNN-THOMPSON, ERIC |
分类号 |
A61K48/00;A61K31/7088;A61K35/76;A61K38/22;A61P5/28;A61P13/08;A61P15/00;A61P15/08;A61P35/00;(IPC1-7):A61K38/16 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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