发明名称 |
Methods of identifying modulators of the estrogen receptor |
摘要 |
The present invention discloses the mechanism of tamoxifen mediated inhibition of acidification. This mechanism information is then used to design methods of identifying compounds that will have the pharmaceutical effect of tamoxifen without the corresponding side-effects.
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申请公布号 |
US6204067(B1) |
申请公布日期 |
2001.03.20 |
申请号 |
US19990335457 |
申请日期 |
1999.06.17 |
申请人 |
BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY |
发明人 |
SIMON SANFORD M.;SCHINDLER MELVIN S.;CHEN YU |
分类号 |
G01N21/64;G01N21/80;G01N33/74;(IPC1-7):G01N31/22;G01N33/48;C07C211/04 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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