发明名称 |
Mammoglobin, et sekrert brystspesifikt brystkreftprotein |
摘要 |
<p>A purified and isolated DNA sequence and the encoded mammary-specific secreted protein, mammaglobin, are disclosed. Also disclosed are methods for detecting breast cancer based upon the overexpression and secretion of mammaglobin by breast cancer cells. The methods detect and/or quantitate the presence of mammaglobin or the mRNA encoding mammaglobin. Immunotherapy-based methods for treating a breast cancer patient with a mammaglobin-expressing tumor are also disclosed. The methods involve using mammaglobin antigens to induce a humoral and/or cell-mediated immune response against the tumor.</p> |
申请公布号 |
NO20011394(D0) |
申请公布日期 |
2001.03.19 |
申请号 |
NO20010001394 |
申请日期 |
2001.03.19 |
申请人 |
WASHINGTON UNIVERSITY |
发明人 |
WATSON, MARK A;FLEMING, TIMOTHY P |
分类号 |
G01N33/53;A61K38/00;A61K39/00;C07K14/47;C12N15/09;C12Q1/68;G01N33/566;G01N33/574;G01N33/577;(IPC1-7):C07H |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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