发明名称 PHARMACEUTICAL COMPOSITIONS
摘要 medicine, pharmacy. SUBSTANCE: invention relates to preparing cyclosporin preparations. Invention claims the preparation comprising cyclosporin, propylene carbonate, surface-active substance with value of hydrophilic-lipophilic balance 8-17 and at least one compound taken among the group including ester of fatty acid and primary alcohol, fatty acid triglyceride of mean long chain and fatty acid monoglyceride as a lubricant. By the second variant the preparation comprises cyclosporin and propylene carbonate. Invention ensures to prepare medicinal form of cyclosporin retaining stability for the total period of their storage being without any alternation of their availability and therefore the effect of cyclosporin can maintain at the constant level. EFFECT: improved properties of compositions. 10 cl, 4 tbl, 19 ex
申请公布号 RU2185188(C2) 申请公布日期 2002.07.20
申请号 RU19990121398 申请日期 1998.03.12
申请人 NOVARTIS AG 发明人 VU JONG SU
分类号 A61K9/107;A61K9/48;A61K38/00;A61K38/13;A61K47/08;A61K47/10;A61K47/14;A61K47/22;A61P37/00;(IPC1-7):A61K38/13 主分类号 A61K9/107
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