| 发明名称 |
METHOD FOR THE PREPARATION OF CITALOPRAM |
| 摘要 |
Method for the preparation of citalopram comprising reaction of a compound of Formula (IV) wherein R is halogen, or CF3-(CF2)n-SO2-, n being 0 to 8, with a cyanide source in the presence of a palladium catalyst and a catalytic amount of Cu<+> or Zn<2+>, or with Zn(CN)2 in the presence of a palladium catalyst.
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| 申请公布号 |
WO0013648(B1) |
申请公布日期 |
2001.03.15 |
| 申请号 |
WO1999DK00640 |
申请日期 |
1999.11.22 |
| 申请人 |
H. LUNDBECK A/S;PETERSEN, HANS;ROCK, MICHAEL, HAROLD;SVANE, HENRIK |
发明人 |
PETERSEN, HANS;ROCK, MICHAEL, HAROLD;SVANE, HENRIK |
| 分类号 |
A61K31/343;A61P25/24;A61P29/00;C07B61/00;C07D307/81;C07D307/87;(IPC1-7):C07D307/87 |
主分类号 |
A61K31/343 |
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