| 发明名称 |
IRON CHELATORS AND USES THEREOF |
| 摘要 |
The present invention provides 2-pyridylcarboxaldehyde isonicotinoyl hydrazo ne (PCIH) analogues suitable for use as in vivo iron chelators, the PCIH analog ue having Formula (1) wherein R1 is an aromatic or heterocyclic group and R2 is either H or OH; isomers thereof or salts thereof; pharmaceutical composition s containing the analogues; and uses of the analogues in the treatment of iron - overload diseases.
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| 申请公布号 |
CA2383721(A1) |
申请公布日期 |
2001.03.15 |
| 申请号 |
CA20002383721 |
申请日期 |
2000.09.04 |
| 申请人 |
UNIVERSITY OF QUEENSLAND;THE HEART RESEARCH INSTITUTE LIMITED |
发明人 |
BECKER, ERIKA MICHELLE;BERNHARDT, PAUL VINCENT;RICHARDSON, DES |
| 分类号 |
A61K31/4402;A61K31/4436;A61K31/4439;A61K31/444;A61P3/00;A61P7/00;A61P39/04;A61P43/00;C07D213/53;C07D213/81;C07D405/12;C07D409/12;(IPC1-7):A61K31/440;C07D401/12;A61K31/443;C07D213/77 |
主分类号 |
A61K31/4402 |
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