发明名称 PHYSICALLY STABLE AND X-RAY AMORPHOUS FORM OF HYDROCHLORIDE RANITIDINE HAVING AN INCREASED ANTI-ULCER ACTIVITY AND METHOD FOR PRODUCING THE SAME
摘要 The present invention relates to a new and formerly known form of hydrochloride ranitidine having H2-blocking properties. This form is X-ray amorphous, substantially differs from the formerly known crystalline modifications due to its characteristics, and also exhibits an enhanced anti-ulcer effect. This X-ray amorphous form is physically stable and can be used in medicine. This invention also relates to a method for producing this X-ray amorphous form from formerly known crystalline modifications.
申请公布号 WO0010562(A8) 申请公布日期 2001.03.15
申请号 WO1998RU00269 申请日期 1998.08.18
申请人 LEONIDOV, NIKOLAI BORISOVICH;USPENSKAYA, SVETLANA IGOREVNA;KRASNOKUTSKY, ALEXANDR BORISOVICH 发明人 LEONIDOV, NIKOLAI BORISOVICH;USPENSKAYA, SVETLANA IGOREVNA;KRASNOKUTSKY, ALEXANDR BORISOVICH
分类号 A61K31/34;A61K9/14;A61P31/00;(IPC1-7):A61K31/34 主分类号 A61K31/34
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