发明名称 |
PHYSICALLY STABLE AND X-RAY AMORPHOUS FORM OF HYDROCHLORIDE RANITIDINE HAVING AN INCREASED ANTI-ULCER ACTIVITY AND METHOD FOR PRODUCING THE SAME |
摘要 |
The present invention relates to a new and formerly known form of hydrochloride ranitidine having H2-blocking properties. This form is X-ray amorphous, substantially differs from the formerly known crystalline modifications due to its characteristics, and also exhibits an enhanced anti-ulcer effect. This X-ray amorphous form is physically stable and can be used in medicine. This invention also relates to a method for producing this X-ray amorphous form from formerly known crystalline modifications.
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申请公布号 |
WO0010562(A8) |
申请公布日期 |
2001.03.15 |
申请号 |
WO1998RU00269 |
申请日期 |
1998.08.18 |
申请人 |
LEONIDOV, NIKOLAI BORISOVICH;USPENSKAYA, SVETLANA IGOREVNA;KRASNOKUTSKY, ALEXANDR BORISOVICH |
发明人 |
LEONIDOV, NIKOLAI BORISOVICH;USPENSKAYA, SVETLANA IGOREVNA;KRASNOKUTSKY, ALEXANDR BORISOVICH |
分类号 |
A61K31/34;A61K9/14;A61P31/00;(IPC1-7):A61K31/34 |
主分类号 |
A61K31/34 |
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地址 |
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