| 摘要 |
<p>The invention relates to compounds of formula (I) wherein R1 is a 5 or 6 membered heteroaryl group, optionally substituted and optionally linked to the pyrazole ring via an alkylene or alkenyle group, or is phenyl, optionally substituted or is -O(CH¿2?)nphenyl, benzofuryl, indolyl or benzothiophenyl, or is -S-lower alkyl; R?2 and R4¿ are independently from each other hydrogen, cyano or -S(O)¿2?-phenyl; R?3¿ is hydrogen, halogen or is heteroaryl or phenyl, optionally substituted -NR'R' or -O-phenyl, or is -benzo[1,3]dioxolyl, -1H-indol-5-yl, naphthyl, benzofuran-2-yl, 1,3,4,9-tetrahydro-b-carbolin-2-yl, piperidin-1-yl, pyrrolidin-1-yl, piperazin-4-yl-methyl or morpholinyl; R5 is -NR¿2?, n is 0-4 and their pharmaceutically acceptable salts. These compounds are adenosine receptor ligands.</p> |
