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发明名称 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE
摘要 The present invention is directed to compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
申请公布号 WO0117992(A1) 申请公布日期 2001.03.15
申请号 WO2000US24542 申请日期 2000.09.07
申请人 MERCK & CO., INC.;BELL, IAN, M.;GALLICCHIO, STEVEN, N.;BESHORE, DOUGLAS, C.;LUMMA, WILLIAM, C., JR.;SISKO, JOHN, T.;ZARTMAN, C., BLAIR 发明人 BELL, IAN, M.;GALLICCHIO, STEVEN, N.;BESHORE, DOUGLAS, C.;LUMMA, WILLIAM, C., JR.;SISKO, JOHN, T.;ZARTMAN, C., BLAIR
分类号 A61K31/335;A61K31/40;A61K31/4178;A61K31/4439;A61K31/454;A61K31/4709;A61K31/496;A61K31/5355;A61K41/00;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D409/14;C07D417/14;C07D513/04;(IPC1-7):C07D403/02;C07D215/20;C07D401/02;A61K31/417;A61K31/443;A61K31/470;A61K31/535 主分类号 A61K31/335
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