| 摘要 |
PURPOSE: The use of a bisphosphonate is provided to manufacture a medicament for the treatment of Osteogenesis imperfecta. CONSTITUTION: In the use of a bisphosphonate for manufacturing a medicament for the treatment of Osteogenesis imperfecta, the bisphosphonate is administered in the first stage and the bisphosphonate is not administered in the second stage, wherein the first stage is for obtaining a defined bone mineral density and the second stage is for architectonic expansion of the bone. At this time, the defined bone mineral density is represented by a cortical mineral density, preferably a volumetric mineral density of the cortical substance.
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