| 发明名称 |
4-CARBOXYIMIDAZOLDERIVATE ALS ANGIOTENSIN-II- ANTAGONISTEN UND IHRE THERAPEUTISCHE VERWENDUNG |
| 摘要 |
<p>Compounds of formula (I): <CHEM> [in which: R<1> is hydrogen, alkyl, cycloalkyl or alkanoyl; R<2> is a single bond, alkylene or alkylidene; R<3> and R<4> are each hydrogen or alkyl; R<6> is carboxy or tetrazol-5-yl; and X is oxygen or sulphur]; and pharmaceutically acceptable salts and esters thereof are AII antagonists and can be used for the treatment and prophylaxis of hypertension and cardiovascular diseases.</p> |
| 申请公布号 |
AT199548(T) |
申请公布日期 |
2001.03.15 |
| 申请号 |
AT19930304131T |
申请日期 |
1993.05.27 |
| 申请人 |
SANKYO COMPANY LIMITED |
发明人 |
YANAGISAWA, HIROAKI;SHIMOJI, YASUO;AMOMIYA, YOSHIYA;KANAZAKI, TAKURO;KOIKE, HIROYUKI;SADA, TOSHIO |
| 分类号 |
A61K31/415;A61K31/41;A61K31/4164;A61K31/4174;A61P9/00;A61P9/12;A61P43/00;C07D233/00;C07D233/66;C07D233/90;C07D403/10;C07D405/12;C07D405/14;(IPC1-7):C07D233/90 |
主分类号 |
A61K31/415 |
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