| 发明名称 |
USING QUATERNARY AMMONIUM SALTS FOR TRANSDERMAL DRUG DELIVERY |
| 摘要 |
A transdermal drug delivery system is disclosed, which includes a polymer, a drug and an amount of a quaternary ammonium salt that is sufficient to act as a penetration enhancer. The quaternary ammonium salt may also be present in an amount sufficient to act as an irritation reducer. Further, the transdermal drug delivery system may also contain a co-enhancer, which provides a synergistic skin permeation enhancing effect when combined with the quaternary ammonium salt. A method for enhancing the transdermal delivery of a drug is also disclosed.
|
| 申请公布号 |
WO0117472(A1) |
申请公布日期 |
2001.03.15 |
| 申请号 |
WO2000US24690 |
申请日期 |
2000.09.08 |
| 申请人 |
WATSON PHARMACEUTICALS, INC. |
发明人 |
FIKSTAD, DAVID;EBERT, CHARLES, D.;VENKATESHWARAN, SRINIVASAN;NILSSEN, LAWRENCE, R. |
| 分类号 |
A61K9/70;A61K31/216;A61K31/4468;A61K31/506;A61K31/522;A61K31/565;A61K31/568;A61K31/57;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/22;A61K47/30;A61K47/32;A61K47/34;A61P1/04;A61P1/08;A61P1/12;A61P3/04;A61P3/06;A61P3/10;A61P3/14;A61P5/00;A61P5/14;A61P7/02;A61P7/10;A61P9/00;A61P17/00;A61P17/02;A61P17/04;A61P19/00;A61P23/02;A61P25/00;A61P25/02;A61P25/06;A61P25/08;A61P25/14;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P29/00;A61P31/04;A61P35/00;A61P37/00;A61P37/06;A61P37/08;A61P43/00;(IPC1-7):A61F13/00 |
主分类号 |
A61K9/70 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
