<p>There is a need for effective oral vaccine adjuvants. Saponin extracts are effective adjuvants but are toxic, so purified saponins have previously been suggested. The invention provides food grade saponins for use as oral adjuvants. This avoids the toxicity problems of the crude extracts and the expense problems of the purified saponin extracts and fractions, whilst simultaneously utilising substances which already have approval for human ingestion.</p>
申请公布号
WO0117555(A2)
申请公布日期
2001.03.15
申请号
WO2000GB03492
申请日期
2000.09.11
申请人
THE DOW CHEMICAL COMPANY;BRENNAN, FRANK, R.;HAMILTON, WILLIAM, D., O.