| 摘要 |
Disclosed are novel nucleoside derivatives of general formula (I), wherein R1 represents a nucleobase or a nucleobase that is provided with at least one protective group, R2 means an H atom or a diisopropylamino-(2-cyanoethoxy)-phosphinyl group, R3 is an H atom or an alkyl radical with up to 4 C atoms, R4 represents an H atom, a nitro group or an alkyl radical with up to 4 C atoms, R5 and R6, independently from each other, mean an H atom, an alkyl radical with up to 4 C atoms or an alkoxy radical with up to 4 C atoms or together represent a methylenedioxy group and R7 is an H atom or an alkyl radical with up to 4 C atoms. The novel nucleoside derivatives can easily be split by means of UV light and are used for the synthesis of oligonucleotides. |
