摘要 |
PROBLEM TO BE SOLVED: To provide a production process for levodione of high purity in high yield by a microorganism. SOLUTION: In a solvent of water, a water-miscible organic solvent or a mixture of water with a water-miscible organic solvent, 2,6,6-trimethyl-2- cyclohexene-1,4-dione is allowed to come into contact with a kind of yeast that can converts 2,6,6-trimethyl-2-cyclohexene-1,4-dione to (6R)-2,2,6-trimethyl- cyclohexane-1,4-dione (levodione), then allowed to contact with Saccharomyces rouxii or Zygosaccharomyces rouxii, and then, the objective levodione is isolated from the reaction medium.
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