发明名称 |
2-alkylidene hydroxycumaranone derivatives |
摘要 |
Compounds of the formulawherein R,R', A,B,T and x have the meaning given in the specification possess uPA (urokinase-type plasminogen activator) antagonist activity and can be employed as antitumor and/or antimetastatic agents.
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申请公布号 |
US6200989(B1) |
申请公布日期 |
2001.03.13 |
申请号 |
US19990401403 |
申请日期 |
1999.09.22 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
DE CILLIS GIANPIERO;DI DOMENICO ROBERTO;KOENIC BERNHARD;OLIVA AMBROGIO |
分类号 |
A61K31/343;A61K31/443;A61K31/4433;A61K31/4525;A61K31/496;A61P35/00;C07D307/83;C07D405/12;C07D405/14;C07D409/14;(IPC1-7):A61K31/452 |
主分类号 |
A61K31/343 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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