发明名称 |
Pkd constructs and screening methods |
摘要 |
The invention provides an isolated nucleic acid molecule comprising the complete open reading frame of the <I>C. elegans pkd-2</I> gene. The invention further provides assay methods for use in the identification of compounds which affect the activity of PKD2 and genetic suppressors of <I>pkd-2</I>, which methods are based on correction of an altered mating phenotype observed in male <I>C. elegans</I> which either overexpress the PKD2 protein or carry a deletion mutation in the <I>pkd-2</I> gene. |
申请公布号 |
AU5401500(A) |
申请公布日期 |
2001.03.13 |
申请号 |
AU20000054015 |
申请日期 |
2000.06.02 |
申请人 |
DEVGEN N.V. |
发明人 |
TITUS KALETTA;ANTON VAN GEEL;THIERRY BOGAERT;MARC VAN DE CRAEN |
分类号 |
A01K67/033;C07K14/47;C12Q1/68 |
主分类号 |
A01K67/033 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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