摘要 |
The present invention relates to the use of reversible selective inhibitors of monoamine oxydase A (MAO-A), reversible selective inhibitors of monoamine oxydase B (MAO-B) or reversible mixed inhibitors of monoamine oxydase A and B (MAO-A and MAO-B) in the manufacture of drugs intended for the treatment of obesity: more specifically, the inhibitors are 3(S),3a(S)-3-methoxymethyl-7- 4,4,4-trifluorobutoxy-3,3a,4,5-tetrahydro-1H-oxazolo 3,4-aquinolin-1-one, (R)-5-(methoxymethyl)-3- 6-(4,4,4-trifluorobutoxy)benzofuran-3-yloxazolidin-2-one and (R)-5-methoxymethyl-3-(6-cyclopropylmethoxybenzofuran-3-yl)oxazolidin- 2-one, (S)-5-methoxymethyl-3- 6-(4,4,4-trifluorobutoxy)-1,2-benzisoxazol-3-yloxazolidin-2-one, lazabemide, milacemide, caroxazone, IFO, befloxatone, moclobemide, brofaromine, phenoxathine, esuprone, befol, RS 8359 (Sankyo), T794 (Tanabe), KP 9 (Krenitsky, USA), E 2011 (Eisei), toloxatone, pirlindole, amiflamine, sercloremine and bazinaprine. The examples give befloxatone. |