| 发明名称 |
Antisense inhibition of SHP-2 expression |
| 摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of SHP-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding SHP-2. Methods of using these compounds for modulation of SHP-2 expression and for treatment of diseases associated with expression of SHP-2 are provided.
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| 申请公布号 |
US6200807(B1) |
申请公布日期 |
2001.03.13 |
| 申请号 |
US19990358683 |
申请日期 |
1999.07.21 |
| 申请人 |
ISIS PHARMACEUTICALS INC. |
发明人 |
BENNETT C. FRANK;COWSERT LEX M. |
| 分类号 |
C12N15/09;A61K31/7088;A61K31/7125;A61K38/00;A61K48/00;A61P3/10;A61P29/00;C07H21/00;C12N15/113;C12Q1/68;(IPC1-7):C07H21/02;C07H21/04;C12P19/34;A01N43/04 |
主分类号 |
C12N15/09 |
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