发明名称 |
Amplifying sequences, vectors comprising these sequences and their uses in compositions for the expression of nucleotide sequences in transfected cells therapeutic and vaccine applications |
摘要 |
Amplifying sequences, vectors comprising these sequences and their uses in compositions for the expression of nucleotide sequences in transfected cells, therapeutic and vaccine applications.Amplifying sequences showing a homology of at least 90% with the following SEQ ID N° 1 sequence:TCTATAAATA X1X2X3GC Y1Y2Y3GG TATTTGGGGT TGGCAGCTGT T in which:X1, X2 and X3 may independently represent respectively C or G, C or G, and C or AY1, Y2 and Y3 may independently represent respectively T or C, C or G, and T or C.Such sequence may included in a sequence or expression vector containing in addition a sequence coding for a protein and a promoter.Such sequences allow very strong amplification of the transcription of the gene coding for the protein.
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申请公布号 |
US6201115(B1) |
申请公布日期 |
2001.03.13 |
申请号 |
US19980191521 |
申请日期 |
1998.11.13 |
申请人 |
INSTITUT PASTEUR;UNIVERSITE PARIS 7 |
发明人 |
PAULIN DENISE;LI ZHEN LIN |
分类号 |
C12N15/09;A61K38/00;A61K38/27;A61K39/13;A61K39/29;A61K48/00;A61P1/16;A61P31/04;A61P31/12;A61P37/04;C12N1/21;C12N15/67;C12N15/85;C12P21/02;C12R1/19;(IPC1-7):C07H21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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