发明名称 CONTROLLED RELEASE COMPOSITIONS FOR INTERFERON BASED ON PEGT/PBT BLOCK COPOLYMERS
摘要 The invention discloses a pharmaceutical composition for the controlled release of relatively toxic active compounds, in particular for bioactive proteins from the class of interferons. The composition comprises a biodegradable block copolymer constructed from poly(ethylene glycol) terephthalate (PEGT) and poly(butylene terephthalate) (PBT). The composition is provided in the form of injectable microparticles, of an in-jectable liquid which may have self-gelling properties, or of a solid implant. The inven-tion further provides a pharmaceutical kit comprising the composition, methods for pre-paring the composition, and the pharmaceutical uses relating thereto.
申请公布号 KR20070118225(A) 申请公布日期 2007.12.14
申请号 KR20077018068 申请日期 2007.08.06
申请人 OCTOPLUS SCIENCES B.V. 发明人 BECHET ANNE CHANTAL;VAN DIJKHUIZEN RADERSMA RIEMKE;STIGTER MARTIN;BEZEMER JEROEN MATTIJS
分类号 A61K9/08;A61K9/16;A61K38/21;A61K47/34 主分类号 A61K9/08
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