发明名称 |
COMPOUND ASSAY USING NEMATODES |
摘要 |
The invention provides methods of screening compounds for potential pharmacological activity using nematode worms, principally but not exclusively the nematode <i>C. elegans</i>. Specifically, the invention relates to the use of nematodes modified to have certain characteristics which provide advantages for compound screening, such as constitutive pharyngeal pumping, increased gut permeability or altered gut molecular transport. Methods for selecting suitably modified nematodes from a population of nematodes are also provided.
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申请公布号 |
WO0063425(A3) |
申请公布日期 |
2001.03.08 |
申请号 |
WO2000IB00557 |
申请日期 |
2000.04.14 |
申请人 |
DEVGEN NV;VERWAERDE, PHILIPPE;FEICHTINGER, RICHARD;BEGHYN, MYRIAM;BOGAERT, THIERRY |
发明人 |
VERWAERDE, PHILIPPE;FEICHTINGER, RICHARD;BEGHYN, MYRIAM;BOGAERT, THIERRY |
分类号 |
A01K67/033;C12N5/10;C12N15/01;C12Q1/02;G01N33/15;G01N33/50;(IPC1-7):C12Q1/02;C12Q1/18;C12Q1/04;C12N15/00 |
主分类号 |
A01K67/033 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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