摘要 |
<p>Biscyclopropanecarboxylic acid amide compounds represented by general formula (I) and NF-kappa B activation inhibitors, inflammatory cytokine production inhibitors, matrix metalloprotease production inhibitors, inflammatory cell adhesion factor expression inhibitors and antiinflammatory agents, antirheumatic agents, immunosuppressors, cancer metastasis inhibitors or antiviral agents containing the above compounds as the active ingredient: (I) wherein R1 to R4 represent each methyl, etc.; R5 and R6 represent each hydrogen, etc.; andUS0023405sent a group represented by one of general formulae (II) to (V): wherein B1 to B10 represent each an aromatic ring or an aromatic heterocycle; and -X1- to -X6- represent each an interatomic bond, etc.</p> |