TRICYCLIC COMPOUNDS AND THEIR USES AS ANTIARRHYTHMIC ANTIFIBRILLATORY AND DEFIBRILLATORY AGENTS

摘要

A compound having a general formula (II) wherein R1 is saturated or unsaturated alkyl, amino-alcohol, diamino, cycloalkyl, and C(=O)(CH2)nNR'R'', (CH2)nCHOHCH2NR'R'', wherein n is an integer; RQ, RT, R', and R'' are each independently a hydrogen, halogen, hydroxyl, saturated, unsaturated, aliphatic, or branched alkyl, substituted or unsubstituted (CH2)m-(hetero)aryl, and sulfonylamide; q andt are each an integer independently selected from 1-4; and pharmaceutically acceptable salts thereof, and the new therapeutic uses thereof and similar compounds as defibrillating, and/or anti-fibrillatory, and/or anti-arrhythmic and/or anti-ischemic drugs.