| 发明名称 |
NOVEL PROCESS FOR THE PRODUCTION OF AMORPHOUS [R-(R*,R*)]-2-(4-FLUOROPHENYL)-BETA,DELTA-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1-HEPTANOIC ACID CALCIUM SALT (2:1) |
| 摘要 |
<p>A novel process for the preparation of amorphous atorvastatin is described where crystalline Form I atorvastatin is dissolved in a non-hydroxylic solvent and after removal of the solvent affords amorphous atorvastatin.</p> |
| 申请公布号 |
EP0839132(B1) |
申请公布日期 |
2001.03.07 |
| 申请号 |
EP19960924553 |
申请日期 |
1996.07.16 |
| 申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
LIN, MIN;SCHWEISS, DIETER |
| 分类号 |
A61K31/00;A61K31/40;A61P3/00;A61P3/06;C07D207/34;(IPC1-7):C07D207/34 |
主分类号 |
A61K31/00 |
| 代理机构 |
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